Increased levels of 5′,8-Cyclopurine DNA lesions in inflammatory bowel diseases
نویسندگان
چکیده
منابع مشابه
Increased Prevalence of Methanosphaera stadtmanae in Inflammatory Bowel Diseases
BACKGROUND The gut microbiota is associated with the modulation of mucosal immunity and the etiology of inflammatory bowel diseases (IBD). Previous studies focused on the impact of bacterial species on IBD but seldom suspected archaea, which can be a major constituent of intestinal microbiota, to be implicated in the diseases. Recent evidence supports that two main archaeal species found in the...
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Objectives: The aims of the present study are: assessing the frequency of lesions in the upper digestive tract in inflammatory bowel diseases, endoscopic and histological characterization of these lesions and revealing their significance in the evolution of patients with inflammatory bowel disease. REZUMAT Leziuni de tub digestiv superior in bolile inflamatorii intestinale Obiective: Studiul de...
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8,5' cyclopurine deoxynucleosides (cPu) are locally distorting DNA base lesions corrected by nucleotide excision repair (NER) and proposed to play a role in neurodegeneration prevalent in genetically defined Xeroderma pigmentosum (XP) patients. In the current study, purified recombinant helicases from different classifications based on sequence homology were examined for their ability to unwind...
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In the course of Inflammatory Bowel Disease (IBD), the possibility of an increase of pancreatic enzymes has been described, almost always justified with their release by the inflamed bowel. Unusually an acute pancreatitis presents itself as a pathology associated to the IBD, probably with a common pathogenetic mechanism. We report the case of a 25 year old man with fever, epigastralgia and a mi...
متن کامل[Inflammatory bowel diseases]
OBJECTIVE: To present a review about inflammatory bowel diseases in childhood so that pediatricians become familiar with two diseases (ulcerative colitis and Crohn s disease) that are increasing in incidence. METHODS: Articles of specific gastroenterological journals were analyzed. Information was also obtained from the author s extensive professional experience in the area. RESULTS: The two di...
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ژورنال
عنوان ژورنال: Redox Biology
سال: 2020
ISSN: 2213-2317
DOI: 10.1016/j.redox.2020.101562